Mississippi Medicaid: Gainwell Technologies

Please follow the Enrollment Instructions below to become an electronic submitter for Mississippi Medicaid.


Required Documents for those applying for new Submitter IDs

The following process must be followed prior to initiation of electronic claim submission or inquiry. Mississippi Medicaid has created the following  guide on how to enroll:

Trading Partner Enrollment and Registration Process

If the link above does not work properly, please download the guide from here:

If you have any questions regarding the enrollment instructions, please call the Mississippi Medicaid EDI Technology Support Center at: 1-800-884-3222.


We can now process 276/277 requests (claim status). If this is a transaction you would like to utilize please make sure to enroll with the payer.


EDI Enrollment Process

Step 1: Enrollment via the "Trading Partner Enrollment" link on their website: https://portal.ms-medicaid-mesa.com/ms/provider/Home/tabid/135/Default.aspx

  • Please make sure your information matches what's in Medicaid's system

  • When selecting Transaction Sets:

    • ​837P Professional = CMS 1500 Claims

    • 837I Institutional = UB 04 Claims

  • ​Please make sure the signature belongs to the authorized representative Medicaid has in their system for your company

  • Once you've completed enrollment, please write down the Trading Partner ID and password listed on that screen. You should receive an email with that information as well

Step 2: Register as a Trading Partner via the "Register Now" link: https://portal.ms-medicaid-mesa.com/ms/provider/Home/tabid/135/Default.aspx

  • Please make sure to select "Trading Partner" on the first screen

  • On the following screen you will need to enter the Trading Partner ID you received from Step 1 and enter your zip code

  • Please write down the User ID and Password you create on the next screen

  • After completing the rest of the required fields on this page, you will receive an email that contains a secure link to complete registration


Waiting for a Response

Once the Trading Partner Enrollment process has been completed, you should receive an email with your login and password for their test site. If you don't receive your credentials within 2-3 weeks, please call their Technology Support Center toll-free at 1-800-884-3222.



Once you have received your Submitter ID and Password from Mediciad, please call the ClaimShuttle Support Team and set an appointment for a Mailbox setup and Test Transmission.

Please have 25 test claims ready for testing. Test files should consist of a variety of claims that represent the type of claims you will be submitting once production status is achieved. Test claims will not be processed for payment but will be validated against production files; therefore, they must contain valid patient procedure, diagnosis, and provider information. Medicaid requires two test batches be successfully submitted in order to receive production approval.